Senior Great Dane Limping Is It Serious

ℹ️Joshua asks about their dog, Zeus
🗓️Asked on 5 December 2025
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Dr Karyn
Dr Karyn Kanowski BVSc, MRCVS

Small Animal Veterinarian

Dr. Karyn is a small animal veterinarian originally from Australia, now based in the UK. She holds degrees in Veterinary Science (2010) and Zoology. When not helping pets, she tends to her 5 cats, 5 dogs, and garden!

The Question

My beloved 13-year-old Great Dane, Zeus, has started limping and seems to be in pain. He's always been such a stoic dog, so seeing him this way is very upsetting. I know Great Danes can be prone to certain health issues, and I'm starting to worry about the worst. Could this be a sign of bone cancer, or is this something else entirely? How serious is this for a dog his age?

Quick Info about Zeus

Age: 13 years
Sex: Male
Neutered/Spayed: Yes
Breed: Great Dane
Weight: 77 lbs
Location: United States
Dr Karyn
Dr. Karyn replied on 8 December 2025

📹 Vet's Video Reply (scroll down to see text answer)

Hi Joshua, Wow – a 13 year-old Great Dane! That is impressive! These gentle giants often don’t make it to double digits, so you’re obviously doing something right. Like most giant breeds, the Great Dane can definitely suffer from joint problems like arthritis, and bone cancer is also on the list of possible concerns. The fact that he is worse after rest makes me more suspicious that arthritis is the culprit here, but Zeus needs to be examined in order to work out what’s going on and exactly how to proceed. If he’s not on them already, it would be a great idea to get Zeus on some joint supplements, but I would imagine that your vet will also want to prescribe some anti-inflammatory pain relief; something I would be strongly recommending. Although anti-inflammatories can have side effects on the gastrointestinal system and put extra pressure on the kidneys, the way I would be looking at it is that Zeus has already had quantity of life, now it’s time to prioritise quality of life. Dogs don’t always tell us when they’re in pain, so for Zeus to be crying out tells me that he’s really having a tough time, so don’t waste any time getting him an appointment. In the meantime, keep him rested, only taking him out to go to the toilet. All the best, Dr Karyn

Disclaimer: The advice provided here is for informational purposes only and does not constitute a medical diagnosis. Always consult your local vet for emergencies.
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